Question

Assertion: Secreted mucus in cystic fibrosis become thick which plugs the passage of the tracts and ducts in the body

Reason: Cystic fibrosis is caused by dysfunctional chloride ion channel due to an altered gene

• A. Both assertion and the reason are true and the reason is a correct explanation of the assertion
• B. Both the assertion and reason are true but the reason is not the correct explanation of the assertion
• C. Assertion is true but the reason is false
• D. Both the assertion and reason are false

Answer 1

The correct option is A Both assertion and the reason are true and the reason is a correct explanation of the assertion

Cystic fibrosis is an autosomal recessive disorder associated with a defect in a protein called cystic fibrosis transmembrane conductance regulator (CFTR), which regulates chloride ion transport across the plasma membrane of epithelial cells. The absence of this protein leads to the thickening of mucus which plugs the passage of ducts and tracts. So, both assertion and the reason are true and the reason is a correct explanation of the assertion.