Assertion :Sickel-cell anaemia occurs due to mutation. Reason: Deletions and insertions of base pairs of DNA, causes frame-shift mutations.

Both Assertion and Reason are correct and Reason is the correct explanation for Assertion

No worries! We‘ve got your back. Try BYJU‘S free classes today!

Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion

No worries! We‘ve got your back. Try BYJU‘S free classes today!

Assertion is correct but Reason is incorrect

Right on! Give the BNAT exam to get a 100% scholarship for BYJUS courses

Both Assertion and Reason are incorrect

No worries! We‘ve got your back. Try BYJU‘S free classes today!

Open in App

Solution

The correct option is C Assertion is correct but Reason is incorrect
Sickle anemia is caused by a single missense mutation at a codon 6 of the beta-globin gene, as a result of this mutation, the glutamic acid at position 6 in the normal protein is changed to a valine in the mutant protein. It occurs because of deletion and insertion of a base that codes for Glutamic acid (CUC) and Valine (CAC)
So, the correct option is 'Assertion is correct but reason is incorrect'

Suggest Corrections

Similar questions

H_{2}

H e

(1 + \frac{P b}{R T})

H_{2}

H e

ASSERTION: n-Pentane and n-Hexane belong to a homologous series.

REASON: n-Pentane and n-Hexane belong to the same class of hydrocarbons and they differ by a - $C H_{2}$ - group.

Assertion – The non-fusible impurities present in iron ore are removed by $C a C O_{3}$ .

Reason: $C a C O_{3}$ which decomposes into $C a O$ and $C O_{2}$ . The $C a O$ formed reacts with $S i O_{2}$ to remove silica

{SiO}_{2}

{CaCO}_{3}

CaO

{CaCO}_{3}

{SiO}_{2}

Join BYJU'S Learning Program