Assertion :Special methods are used for transformation i.e., incorporation of recombinant DNA into host. Reason: DNA is a hydrophilic molecule.

Both Assertion and Reason are correct and Reason is the correct explanation for Assertion

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Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion

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Assertion is correct but Reason is incorrect

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Both Assertion and Reason are incorrect

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Solution

The correct option is A Both Assertion and Reason are correct and Reason is the correct explanation for Assertion
Transformation is permanent heritable change in a cell, particularly a bacterial cell, that occurs as a result of its acquiring foreign DNA. But cells normally do not take up foreign DNA molecule because DNA is a hydrophilic macromolecule and its movement through lipid membrane is opposed. Special methods such as Ca $C I_{2}$ treatment, electroporation, particle delivery method, etc., are used to make host cells competent i.e., able to take up foreign DNA.
So, the correct answer is 'Both Assertion and Reason are correct and Reason is the correct explanation for Assertion'.

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