Assertion :T cell actively participates in type IV hypersensitivity reaction. Reason: Type IV is a cell-mediated hypersensitivity reaction.
A
Both Assertion and Reason are correct and Reason is the correct explanation for Assertion
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B
Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion
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C
Assertion is correct but Reason is incorrect
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D
Both Assertion and Reason are incorrect
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Solution
The correct option is A Both Assertion and Reason are correct and Reason is the correct explanation for Assertion
Cell-mediated immunity is an immune response that involves the activation of phagocytes, natural killer cells (NK), antigen-specific cytotoxic T-lymphocytes, and the release of various cytokines in response to an antigen. In type IV hypersensitivity reactions, CD4+ helper T cells recognize antigen in a complex with major histocompatibility complex class II on macrophages. Thus the correct answer is option A.