Assertion :The -As=As- linkage present in arsphenamine (a sulpha drugs) resemles the -N=N- linkage present is azo dyes. Reason: The first antibacterial agent, prontosil resembles in structure to the compound salvarsan.
A
Both Assertion and Reason are correct and Reason is the correct explanation for Assertion
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B
Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion
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C
Assertion is correct but Reason is incorrect
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D
Both Assertion and Reason are incorrect
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Solution
The correct option is B Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion
Sulfa drug, also called sulfonamide, any member of a group of synthetic antibiotics containing the sulfanilamide molecular structure. Sulfa drugs were the first chemical substances systematically used to treat and prevent bacterial infections in humans.
Paul Ehlrich a German bacteriologist was investigating Arsenic based structures in order to produce less toxic substances for the treatment of syphilis. He developed the medicine, arsphenamine, known as salvarsan.Salvarsan is not a sulpha drug.
Ehrlich was working on azodyes. The –As = As– linkage present in arsphenamine resembles the –N = N – linkage present in azodyes in the sense that arsenic atom is present in place of nitrogen.
He also succeeded in preparing the first effective antibacterial agent, prontosil, which resembles in structure to the compound, salvarsan.
Hence,both Assertion and reason are correct but reason is not correct explanation for assertion.