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Question
Assertion :The first clinical gene for ADA therby was given to cure SCID. Reason: The normal gene was delivered into the patient's cells using retroviral vector.
Assertion :The first clinical gene for ADA therby was given to cure SCID. Reason: The normal gene was delivered into the patient's cells using retroviral vector.
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Solution
The correct option is B Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion
SCID ( severe combined immuno-deflciency disease) is an immune disorder
caused due to ADA (adenosine deaminase) deficiency. The patient contains
defective ADA gene thus ADA enzyme becomes deficient. Normal ADA gene
thus ADA enzyme becomes deficient. Normal ADA gene that could function
normally is inserted into the patient's cell. Such process of
introduction of a normal functional gene into cells, which contains the
defective allele of concerned gene with the objective of correcting a
genetic or acquired disorder is called gene therapy. First gene therapy
was done to cure SCID and the normal gene was introduced using
retroviral vector.
So, the correct answer is 'Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion'.
SCID ( severe combined immuno-deflciency disease) is an immune disorder
caused due to ADA (adenosine deaminase) deficiency. The patient contains
defective ADA gene thus ADA enzyme becomes deficient. Normal ADA gene
thus ADA enzyme becomes deficient. Normal ADA gene that could function
normally is inserted into the patient's cell. Such process of
introduction of a normal functional gene into cells, which contains the
defective allele of concerned gene with the objective of correcting a
genetic or acquired disorder is called gene therapy. First gene therapy
was done to cure SCID and the normal gene was introduced using
retroviral vector.
So, the correct answer is 'Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion'.
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