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Krebs Cycle

Assertion :Th...

Question

Assertion :The first step in TCA cycle is the condensation of Pyruvate with oxaloacetic acid and water. Reason: This reaction is catalysed by enzyme pyruvate synthase.

A

Both Assertion and Reason are correct and Reason is the correct explanation for Assertion

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B

Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion

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C

Assertion is correct but Reason is incorrect

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D

Both Assertion and Reason are incorrect

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Solution

The correct option is D Both Assertion and Reason are incorrect
The TCA cycle starts with the condensation of acetyl group with oxaloacetic acid (OAA) and water to yield citric acid. The reaction is catalysed by the enzyme citrate synthetase and a molecule of CoA is released.
Acetyl $C o A + O A A + H_{2} O c i t r a t e - ----- \to s y n t h e t a s e C i t r a t e + C o A$

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