Question

Assertion :The glomerular filtrate resembles the protein free plasma in composition and osmotic pressure.
Reason: The glomerular capillary wall and inner membrane of Bowman's capsule are impermeable to large molecules.

• A. Both Assertion and Reason are correct and Reason is the correct explanation for Assertion
• B. Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion
• C. Assertion is correct but Reason is incorrect
• D. Both Assertion and Reason are incorrect

Answer 1

The correct option is A Both Assertion and Reason are correct and Reason is the correct explanation for Assertion

Glomerular filtrate is the protein free fluid which is filtered from the blood of glomerular capillaries to the lumen of the Bowman's capsule. This process is called glomerular filtration. About one-fifth of the total volume of plasma

flowing through the kidneys is filtered out as the glomerular filtrate. The filtration occurs across the membrane made of the glomerular capillary wall and the inner membrane of the Bowman's capsule. The pores of this following membrane are impermeable to large molecules or particles. large particles like blood cells and protein macromolecules do not normally enter into the glomerular filtrate But smaller molecules like glucose, urea, creatinine, amino acids and mineral salts are filtered into the Bowman's capsule in concentrations more or less similar to their respective concentrations in the plasma. The filtrate therefore almost resembles the protein free plasma in composition and osmotic pressure.

So, the correct answer is 'Both Assertion and Reason are correct and Reason is the correct explanation for Assertion'.