Question

Assertion :Wobble hypothesis explains the phenomena of multiple codons coding for the code for a single amino acid. Reason: One tRNA molecule can recognise and bind to more than one codon, due to the less-precise base pairs.

• A. Both Assertion and Reason are correct and Reason is the correct explanation for Assertion
• B. Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion
• C. Assertion is correct but Reason is incorrect
• D. Both Assertion and Reason are incorrect

Answer 1

The correct option is A Both Assertion and Reason are correct and Reason is the correct explanation for Assertion

Wobble hypothesis gives an account of the degeneracy of the genetic code. Degeneracy means that some amino acids have more than one nucleotide codon specifying them during protein synthesis. According to the Wobble hypothesis, only the first and second bases of the triple codon on 5′ → ‘3 mRNA pair with the bases of the anticodon of tRNA i.e., A with U, or G with C. The pairing of the third base varies according to the base at this position, for example G may pair with U. The conventional pairing (A = U, G = C) is called Watson-Crick pairing and the second abnormal pairing is called wobble pairing. Thus the correct answer is option A.