At the end of prophase:

Cell organelles disappear

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Spindle fibre formation

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Nuclear membrane disappears

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Chromosomes appear

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Solution

The correct option is D Chromosomes appear
Prophase is the first stage of mitosis, during which the nuclear membrane disappears and the nuclear material resolves itself into chromosomes. At the end of prophase, the chromosomes are organised haphazardly. They have one centromere each and are made up of a pair of chromatids.

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At the end of prophase

At the end of prophase, the chromosome exhibit

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