Question

At what pH does pepsin work best?

Answer 1

Pepsin:

1. Pepsin is a stomach enzyme that catalyzes the hydrolysis of protein molecules.
2. The gastric chief cells secrete pepsinogen as the proenzyme.
3. The parietal cells present in the stomach lining secrete HCl, thereby lowering the pH of the stomach.
4. A low pH converts pepsinogen to pepsin.
5. Pepsin works best at pH 1.5-2.