Question

At what stage of the cell cycle are histone proteins synthesized in a eukaryotic cell ?

• A. S-phase
• B. $G_2$-stage of prophase
• C. Prophase
• D. Telophase

Answer 1

The correct option is A S-phase

Histone proteins are the basic proteins that are used to pack DNA into chromosomes.

During S phase of the cell cycle, the histone proteins are synthesized in a eukaryotic cell. The major event in S phase is DNA replication. The goal of this process is to create exactly two identical semi-conserved chromosomes. The cell prevents more than one replication from occurring by loading pre-replication complexes onto the DNA at replication origins during G1​ phase which is dismantled in S phase as replication begins.

So, the correct answer is option B.