Atrial natriuretic factor (ANF) is released in response to the increase in blood volume and blood pressure. Which of the following is not the function of ANF?

Stimulates salt loss in urine.

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Inhibits the release of renin from juxtaglomerular apparatus.

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Stimulates aldosterone secretion.

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Inhibits sodium reabsorption from collecting duct.

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Solution

The correct option is C Stimulates aldosterone secretion.
When there is an increase in blood pressure, ANF is secreted by the atrial walls of the heart. ANF inhibits the reabsorption of sodium in the kidneys and leads to the production of large volumes of urine. ANF is antagonistic to the RAAS mechanism as it causes vasodilation while aldosterone absorbs sodium from glomerular filtrate causing vasoconstriction.

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