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Question

Attachment of spindle fibres to kinetochores of chromosomes becomes evident in:

A
Anaphase
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B
Telophase
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C
Prophase
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D
Metaphase
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Solution

The correct option is D Metaphase
Mitosis is a type of cell division in which a parent cell divides and forms two daughter cells that are identical to the parent cell.

It includes karyokinesis (division of nucleus) and cytokinesis (division of cytoplasm).

Karyokinesis is further divided into four phases: Prophase, metaphase, anaphase and telophase.

During prophase, the chromatin undergoes coiling and packaging to form into compact, short structures known as chromosomes. This is called condensation and it starts in prophase and gets completed by the end of the next phase, the metaphase.

Each chromosome with two sister chromatids is clearly visible in the metaphase.

The chromosomes align at the centre of the cell. The spindle fibres attach to the kinetochore protein present on either side of the centromere of the chromosomes during metaphase.

During the next phase, anaphase, the centromere splits and sister chromatids separate and move to opposite poles. Spindle fibres help to move the daughter chromosomes to opposite poles.

The last phase of mitosis is telophase. During telophase, the chromosomes decondense and lose their individuality. The nuclear envelope develops around the chromosomes at each pole and thus two daughter nuclei are formed.

Hence, option d is correct.

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