Question

Autoimmune diseases arise from the inadvertent recognition of self-antigens by one's own immune system. Which of the following are likely the cause of self-recognition?

• A. Failure of one's immune system to eliminate self-recognizing cells.
• B. Chronic exposure to allergens such as pollen.
• C. Somatic mutations that lead to the creation of self-recognizing cells.
• D. Uncontrolled proliferation of lymphocytes, as in the case of leukemias gives T-cells the ability to recognize self cells.

Answer 1

The correct option is C Somatic mutations that lead to the creation of self-recognizing cells.

Mutations in the T lymphocytes that lead to destruction of healthy cells in the body, that is the immune system treats the body cells as foreign

So, the correct answer is 'Somatic mutations that lead to the creation of self-recognizing cells'