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Question

AZT is used in treatment of

A
Malaria
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B
AIDS
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C
T.B
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D
Kala-azar
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Solution

The correct option is B AIDS
AZT (azidothymidine), also called zidovudine is a anti-retroviral drug used to prevent and treat HIV/AIDS. These drug is used to delay development of AIDS in patient infected with HIV. It belongs to the group of drugs known as nucleoside reserve transciptase inhibitors (NRTIs). It is active agaisnt HIV when the virus is replicating into proviral DNA.Because the active compound zidovudine 5-triphosphate, has a high affinity for an enzyme called reserve transcriptase, which is used by retroviruses such as HIV to replicate viral single-stranded RNA into proviral double-stranded DNA. Hence AZT is used in treatment of AIDS.
So, the correct answer is 'AIDS'.

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