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Question

Base sequence of RNA was described by

A
Watson and Crick
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B
Ephrusil
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C
Holley
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D
Edelman
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Solution

The correct option is C Holley
Robert Willilam Holley was an American biochemist. He shared the Nobel Prize for Medicine with Har Gobind Khorana and Marshall Nirenberg for describing the structure of alanine transfer RNA, linking DNA and protein synthesis. Holley's research on RNA focused first on isolating transfer RNA and later on determining the sequence and structure of alanine tRNA, the molecule that incorporates the amino acid alanine into proteins. Holley's team of researches determined the tRNA's structure by using two ribonucleases to split the tRNA, molecule into pieces.

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