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Question

Basic principle of developing transgenic animals is to introduce the gene of interest into the nucleus of

A
somatic cells
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B
vegetative cell
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C
fertilised egg cell
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D
body cell
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Solution

The correct option is C fertilised egg cell
Transgenic animals are animals (most commonly mice) that have had a foreign gene deliberately inserted into their genome. Such animals are most commonly created by the microinjection of DNA into the pronuclei of a fertilised egg which is subsequently implanted into the oviduct of a pseudopregnant surrogate mother. This results in the recipient animal giving birth to genetically modified offspring.

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