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Question

Because inflammation is a major component of many allergic diseases, notably asthma and atopic dermatitis, therapy includes anti-inflammatory substances such as ________.

A
bradykinin
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B
histamine
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C
corticosteroids
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D
prostaglandins
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Solution

The correct option is C corticosteroids
Inhalation therapy with low-dose corticosteroids reduces inflammation by inhibiting innate immune cell activity and has been used successfully to reduce frequency and severity of asthma attacks. Steroids work by reducing this inflammation and weakening the immune system's overreaction to the allergen.

The inflammatory response occurs due to injury of tissues by toxins, heat, bacteria, etc. The cells that are damages in the process releaase certain inflammation inducing substances such as histamine, bradykinin, and prostaglandins. These chemicals cause blood vessels to leak fluid into the tissues.

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