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Question

Bilirubin and biliverdin are derived from

A
Globin
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B
Heme
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C
Iron
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D
Fat
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Solution

The correct option is B Heme
Bilirubin and biliverdin are derived from heme. The component of haemoglobin responsible for binding oxygen, consists of an iron ion, that binds oxygen and a porphyrin ring, that binds the globin molecules; one molecule binds one molecule of oxygen. Biliverdin results from the breakdown of the heme moiety of hemoglobin in erythrocytes. Bilirubin is the yellow breakdown product of normal heme catabolism, caused by the body's clearance of aged red blood cells which contain hemoglobin.

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