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Question
Blood levels of which of the following substances is decreased in Graves’ disease?
Blood levels of which of the following substances is decreased in Graves’ disease?
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Solution
The correct option is D TSH
In Grave's disease (hyperthyroidism), the thyroid is stimulated to produce and secrete large quantities of thyroid hormones as a result of stimulation by thyroid-stimulating immunoglobulins
(antibodies to the thyroid-stimulating hormone (TSH) receptors on the thyroid gland). Because of the high circulating levels of thyroid hormones, anterior pituitary secretion of TSH is turned off (negative feedback).
In Grave's disease (hyperthyroidism), the thyroid is stimulated to produce and secrete large quantities of thyroid hormones as a result of stimulation by thyroid-stimulating immunoglobulins
(antibodies to the thyroid-stimulating hormone (TSH) receptors on the thyroid gland). Because of the high circulating levels of thyroid hormones, anterior pituitary secretion of TSH is turned off (negative feedback).
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