Question

Both haemophilia and thalassemia are blood related disorders in humans. Write their causes and the difference between the two. Name the category of genetic disorder they both come under. [3]

Answer 1

The following are the causes and difference between haemophilia and thalassemia: [1 mark for each point (any two points)]
$\begin{array}{ccc}\text{Haemophilia}& \text{Thalassemia}& \\ \text{Single protein involved in the clotting of blood is affected}& \text{Defects in the synthesis of globin chain lead to formation of abnormal haemoglobin}& \\ & & \\ \text{Sex linked recessive disorder.}& \text{Autosomal recessive disorder}& \\ \text{Blood does not clot.}& \text{Results in anaemia.}& \end{array}$

Both haemophilia and thalassemia are Mendelian disorders. [1]