Question

Both mast cells and basophils

• A. are phagocytic
• B. circulate in the blood stream
• C. are found primarily in lymph nodes
• D. release histamine

Answer 1

The correct option is D release histamine

A mast cell is a white blood cell which contains granules. Mast cells are found in most tissues such as skin, mucosa, digestive tract, mouth, conjunctiva, nose, etc. which are surrounded by blood vessels and nerves. They are derived from myeloid stem cells and work as a part of the immune system. The granules of the mast cells are filled with histamine and heparin. Thus, mast cells release these chemicals during inflammatory and allergic reactions. Mast cells perform other several functions as well. They are involved in wound healing, angiogenesis, immune tolerance, defense against pathogens, and blood brain barrier function.

Basophil is a white blood cell and a granulocyte. Basophils have granules on their surfaces. These granules are filled with enzymes called histamine and heparin. These enzymes are important in inflammation, allergic reactions and asthma. They are mostly found in the skin and mucosa tissues, which are the lining tissues of openings in the body. Basophils account for 1% of the overall white blood cells in the body.

So, the correct option is 'Option D'.