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Question

Briefly mention the mechanism of action of FSH.

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Solution

Follicle-stimulating hormone (FSH) is a hormone which synthesized and secreted by the gonadotropic cells of the anterior pituitary gland, it regulates the development, growth, and reproductive processes of the human body. FSH shows its effect by binding to its specific receptors present on the ovarian cell membrane. Binding of FSH to its specific receptor present over the cell surface activates an enzyme called adenylate cyclase. This enzyme converts ATP into cyclicAMP. The cyclicAMP is called the second messenger and carries out various biochemical responses in the cell by activating the existing enzyme system in the cell. The biochemical responses then lead to physiological responses like ovarian growth.


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