The correct option is A Mucus and bicarbonates
Brunner's gland is the tubular gland present in the duodenum where the absorption of food takes place and secretes a large amount of mucus and bicarbonates to protect duodenal mucosa and to neutralize the acidic medium of chyme. They open into the crypts of Lieberhhum. Hormone cholecystokinin (CCK) and secretin are also secreted by the duodenum which stimulates secretion of pancreatic juice by pancreas, gall bladder to produce bile juice and formation of bile by the liver and pancreatic juice. Whereas estradiol is the sex hormone secreted by the gonads. Thus, the correct answer is option A.