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Question

By the aerobic respiration of one molecule of glucose, how many CO2 molecules produced in the mitochondria but outside the TCA cycle?

A
2
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B
4
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C
6
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D
12
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Solution

The correct option is C 2
The four steps of aerobic respiration are glycolysis, formation of acetyl coA, TCA cycle and the electron transport chain. In this, glycolysis takes place in the cytoplasm and TCA cycle takes place in the mitochondria. Before entering the TCA cycle, pyruvic acid is converted into acetyl CoA. This process is known as oxidative decarboxylation. During this step, 2 molecules of pyruvic acid lose one carbon atom each with the release of 2 molecules of carbon dioxide. In this step, 2 molecules of NAD+ are converted into 2 molecules of NADH. This step is catalyzed by pyruate dehydrogenase complex. The two molecules of acetyl CoA are then converted into 2 molecules of oxaloacetate, which enter the TCA cycle.
Thus, the correct answer is '2.'

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