Prime factorising 3645, we get,
3645=5×3×3×3×3×3×3
=51×36.
We know, a perfect cube has multiples of 3 as powers of prime factors.
Here, number of 5's is 1 and number of 3's is 6.
So we need to multiply another 52 to the factorization to make 3645 a perfect cube.
Hence, the smallest number by which 3645 must be multiplied to obtain a perfect cube is 52=25.