Question

C-peptide of human insulin is

• A. a part of mature insulin molecule
• B. responsible for the formation of disulphide bridges
• C. removed during maturation of pro-insulin to insulin
• D. responsible for its biological activity

Answer 1

The correct option is C removed during maturation of pro-insulin to insulin

C-peptide of human insulin connects the A and B chain of proinsulin molecule. After the processing of proinsulin to insulin molecule, C-peptide is removed leaving behind A and B chains which bound together by disulphide bonds to constitute an insulin molecule.