Question

C-peptide of human insulin is _________________.

• A. A part of mature insulin molecule
• B. Responsible for formation of disulphide bridges
• C. Removed during maturation of pro-insulin to insulin
• D. Responsible for its biological activity

Answer 1

Answer: (C)

Removed during maturation of pro-insulin to insulin

In mammals, including humans, insulin is synthesised as pro-hormone which needs to be processed before it becomes a fully mature and functional hormone. It contains an extra stretch called the C peptide which is removed during maturation into insulin.