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Question

Ca2+ influx causes extrusion of cortical granuoles and zona reactions which make the zona pellucida impervious to second sperm by destroying sperm receptors.

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Solution

as sperm enter to prevent polysperm calcium influx means calcium move inside ovuum as a result it stimulate cortical granules for extrusion i.e release of its substances out in perivitelline space so as to make zona pellucida impermeable to second sperm by destroying sperm recepto ZP3

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