Hypothalamus and pituitary gland are primary endocrine glands of the human body. Hypothalamus is a small area of the brain, which is located under the thalamus. The pituitary gland is located just below the hypothalamus. The pituitary gland comprises two lobes; anterior lobe (adenohypophysis) and posterior lobe (neurohypophysis). The hypothalamus is connected to the anterior lobe of the pituitary gland by means of a special portal blood system. Moreover, the hypothalamus is directly connected to the posterior lobe of the pituitary gland by means of neurons. Therefore, the hypothalamus regulates the function of the pituitary gland. This is the relationship between hypothalamus and pituitary gland.
(PDF) Relationship Between Hypothalamus and Pituitary Gland. The hypothalamus links the nervous and endocrine systems by way of the pituitary gland. Its function is to secrete releasing hormones and inhibiting hormones that stimulate or inhibit (like their names imply) production of hormones in the anterior pituitary.