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Question

Carbon monoxide emitted by automobiles prevents transport of oxygen in body due to:

A
its combination with oxygen to form carbon dioxide
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B
break down of haemoglobin
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C
preventing haemoglobin to form oxyhaemoglobin
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D
formation of free radicals in the blood
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Solution

The correct option is C preventing haemoglobin to form oxyhaemoglobin

Carbon dioxide and carbon monoxide gases are emitted during the combustion of various fuels. Carbon monoxide is poisonous, whereas carbon-dioxide is non-toxic in nature. Carbon monoxide is poisonous because it is capable of forming a complex with hemoglobin (carboxyhaemoglobin), which is more stable than the oxygen-haemoglobin complex. The concentration range of 3–4% of carboxyhaemoglobin decreases the oxygen-carrying capacity of blood. This results in headaches, weak eyesight, nervousness, and cardiovascular disorders. A more increased concentration may even lead to death.

Carbon monoxide when binds to hemoglobin forms a stable compound - carboxyhaemoglobin. Since, oxygen of carbon monoxide binds more readily to hemoglobin than do Oxygen of carbon dioxide, therefore carbon monoxide prevents carbon dioxide from binding to Hb, which means diffusion or exchange of gases won't take place at alveolar site. So, carbon monoxide is more harmful because it prevents oxygen from entering the body.


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