Question

Carbylamine reaction is shown by:

• A. Quaternary salt
• B. $3^{\circ }$-amine
• C. $2^{\circ }$-amine
• D. $1^{\circ }$-amine

Answer 1

The correct option is D $1^{\circ }$-amine

Carbylamine reaction mechanism includes the addition of amine to the intermediate created from the dehydrohalogenation of chloroform. This intermediate is called dichlorocarbene. The carbylamine reaction is also known as Hoffmann isocyanide synthesis. It is the reaction of a primary amine, chloroform and a base to synthesize isocyanides. The dichlorocarbene intermediate is very important for this conversion. The carbylamine reaction cannot be used to synthesize isocyanides from secondary or tertiary amines.

Carbylamine test is given by $1^{\circ }$ amine with $CHC{l}_3\text{and alc.}KOH$
$RN{H}_2+CHC{l}_3+\text{alc.}KOH\to \stackrel{\oplus }{RN}\equiv \stackrel{\ominus }{C}$
Secondary and tertiary amines don't give carbylamine reaction test.
So, the correct option is (d).