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Question

Cdk which control progression through cell cycle check points are fully activated by.

A
Binding to cyclin
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B
Phosphorylation by Cdk activating protein kinase
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C
Binding to cyclin, plus phosphorylation by Cdk activating protein kinase
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D
Phosphorylation by tyrosine kinase
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Solution

The correct option is C Binding to cyclin, plus phosphorylation by Cdk activating protein kinase

Through phosphorylation, Cdks signal the cell that it is ready to pass into the next stage of the cell cycle. As their name suggests, Cyclin-Dependent ProteinKinases are dependent on cyclins, another class of regulatory proteins. Cyclins bind to Cdks, activating the Cdks to phosphorylate other molecules.

So, the correct option is ‘binding to cyclin, plus, phosphorylation by Cdk activating protein kinases’.

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