Question

Cell disintegration during downstream processing is result of ________.

• A. Stirring of cells, to prevent clumping, for better growth
• B. Rupturing of the cell walls and/or cell membranes to release product of interest formed within the cell
• C. Clumping of cells using chemicals for better separation
• D. None of the above

Answer 1

The correct option is B Rupturing of the cell walls and/or cell membranes to release product of interest formed within the cell

Product of interest in fermentation reaction can be present either inside the cells or outside the cells. If it is inside, the cells must be ruptured to release it out of cell walls and cell membranes. This process is called as cell disintegration.