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Question

Cellular respiration takes place in the mitochondria of eukaryotic cells. Which process is affected when holes are poked through the inner mitochondrial most membrane?

A
Production of pyruvate
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B
Production of Acetyl-CoA
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C
Production of NADH
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D
Production of ATP
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E
Production of lactic acid
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Solution

The correct option is B Production of ATP
If we poke a hole through inner mitochondrial membrane then there will be no proton gradient as the protons will just diffuse through the hole. Since proton gradient is necessary for ATP formation (as stated by chemiosmotic hypothesis), ATP production will be reduced or may be stopped completely.
So, the correct answer is 'Production of ATP'.

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