Question

Central dogma goes topsy-turvy was reported by

• A. Watson
• B. Crick and Temin
• C. Baltimore and Watson
• D. Temin and Baltimore

Answer 1

The correct option is D Temin and Baltimore

Central dogma represents the sequential process of gene expression via four steps. Accordingly, the genetic information present in sequence of deoxyribonucleotides is transcribed into sequence of ribonucleotides in RNA which in turn serve as template to a polypeptide. The genetic information of DNA is self replicated via DNA replication where parent strand serves as template for synthesis of new DNA strands. Thus, transcription uses DNA strand template while translation uses RNA as template. But it is not always a linear process and can go upside down since reverse transcriptase enzyme synthesize DNA using RNA as template. It was first shown by Temin and Baltimore.