Question

Central dogma of genetic information was modified by the discovery of

• A. Reverse transcriptase
• B. DNA polymerase
• C. RNA polymerase
• D. Ligase

Answer 1

The correct option is A Reverse transcriptase

Central dogma was modified by the discovery of reverse transcription.
$DNA\stackrel{Transcription}{\to }RNA\stackrel{Translation}{\to }Protein$
But DNA is synthesised from RNA in retrovirus, the concept was known as reverse transcription was observed by Temin and Baltimore in Rous sarcoma virus. This reaction was catalysed by enzyme reverse transcriptase.