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Question

Centriole/centrosome replication occurs in

A
Early prophase
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B
G1-phase
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C
S-phase
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D
G0-phase
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Solution

The correct option is B G1-phase

Interphase, a phase of the cell cycle, is the one in which a cell spends most of its life. During this phase, the cell copies its DNA in preparation for mitosis. The cell obtains nutrients, uses them to grow and conducts other "normal" cell functions. It was previously known as the resting phase although the cell is preparing for cell division at a later stage. It is divided into three phases:

1. G1 (first gap) - cell grows and functions normally. During G1, the large amount of protein synthesis occurs and the cell grows (to approximately double its original size) - more organelles are produced and the volume of the cytoplasm increases. Also, certain intracellular components, such as the centrosomes undergo replication. It is an intermediate phase occupying the time between the end of cell division in mitosis and the beginning of DNA replication during S phase. During, G1, a review of the cellular environment occurs and only when the cell is ready, it enters the next phase. If not, cells enter G0 phase and can pause indefinitely at this phase.

2. S (synthesis) - the cell duplicates its DNA

3. G2 (second gap) - the cell resumes its growth in preparation for division.

Hence, the correct answer is option B.


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