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B
Single-stranded RNA
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C
Double-stranded DNA
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D
Double-stranded RNA
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Solution
The correct option is C
Double-stranded DNA
The Correct option is C.
Explanation of the correct option:
Chargaff’s rules are based on complementary base pairing between nitrogenous bases of two antiparallel strands of a double-stranded DNA molecule and thus are applicable to double-stranded DNA only.
According to Chargaff’s rule, all cellular DNAs, regardless of the species, the number of adenosine residues is equal to the number of thymidine residues which means that A = T and the number of guanosine residues is equal to the number of cytidine residues; G = C.
Hence, the sum of the purine residues equals the sum of the pyrimidine residues; i.e., A + G = T + C;
Final answer: Chargaff's rule is applicable to double-stranded DNA.