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Question

Choose the correct analogy with respect to the experiment done by the given scientists.

A
Griffith: Transformation:: Hershey and Chase: Replication
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B
Griffith: Transformation:: Hershey and Chase: Transduction
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C
Griffith: Transduction:: Hershey and Chase: Transformation
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D
Griffith: Replication:: Hershey and Chase: Transformation
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Solution

The correct option is B Griffith: Transformation:: Hershey and Chase: Transduction

The bacterial transformation was shown by Frederick Griffith in his experiments on Streptococcus pneumoniae. He took two strains of Streptococcus pneumoniae. They were S(virulent)and R (non-virulent) strains.
Transformation is the genetic alteration of a cell that happens as a result of direct uptake and incorporation of genetic material from the surroundings through the cell membrane.
S-strain was able to cause pneumonia infection in the mouse while R-strain was not. When heat-killed S-strain was mixed with live R-strain, it was able to cause infection in the mouse. He witnessed a miraculous transformation in the bacteria and stated that something was being passed on to the R-strain from the heat-killed S-strain bacteria that transformed it to live S-strain bacteria.

The transduction experiment was done by Alfred Hershey and Martha Chase. In their experiment they have proved that the DNA from bacteriophages was getting transferred into the bacteria by using the radioisotopic technique. They worked with T2 bacteriophages and E.coli bacteria.


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