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Question

Choose the correct answer from the alternatives given :
In a DNA strand the nucleotides are linked together by

A
Glycosidic bonds
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B
Phosphodiester bonds
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C
Peptide bonds
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D
Hydrogen bonds
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Solution

The correct option is B Phosphodiester bonds
A nucleotide has three components - nitrogenous base, a pentose sugar ribose in case of RNA and deoxyribose for DNA) and a phosphate group. There are two types of nitrogenous bases - Purines (Adenine and Guanine) and Pyrimidines (Cytosine and Thymine). A nitrogenous base is linked to the pentose sugar through a N-glycosidic linkage to form a nucleoside. When a phosphate group is linked to 5 -OH of a nucleoside through phosphodiester linkage, a corresponding nucleotide is formed. The nucleotides are linked through 3-5 phosphodiester linkage to form a dinucleotide.
So, the correct answer is 'Phosphodiester bonds'.

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