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Question

Choose the correct answers from the alternatives given :
The phenmomenon known as wobble refers to

A
the movement of multiple ribosomes along the same mRNA
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B
the shifting of the reading frame in a deletion or insertion mutation
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C
the ability of a tRNA to pair with different codons that may differ in the third base
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D
the movement of a tRNA from the A to the P site
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Solution

The correct option is C the ability of a tRNA to pair with different codons that may differ in the third base
According to wobble phenomenon or hypothesis, flexible base pairing at the third position of the codon-anticodon duplex is possible. This means a chance in the third nitrogenous base of a codon doesn't produce a different but same amino acid. Wobble phenomenon or hypothesis, thus, corresponds to the ability of a tRNA to pair with different codons that may differ in the third base. The amino acid also doesn't change.
So, the correct option is 'the ability of a tRNA to pair with different codons that may differ in the third base.'

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