Question

Choose the correct answers from the alternatives given.
Which of the following enzymes has the lowest pH optimum?

• A. Pepsin
• B. Trypsin
• C. Salivary amylase
• D. Pancreatic amylase

Answer 1

The correct option is A Pepsin

• In humans and other mammals pepsin produced in the stomach by chief cells in an inactive form called pepsinogen.
• Once the pepsinogen is released into the stomach, the low pH from the gastric acid helps in the conversion of pepsinogen into pepsin, the active enzyme.
• Many proteins are denatured at low pH, and most enzymes whether or not they denature require a higher pH for activity. Hence, pepsin is the enzymes has the lowest pH optimum.

So, the correct answer is 'pepsin'.