Question

Choose the correct option for the mechanism of enzyme action.

• A. E + S $\rightleftharpoons$ ES $\to$ EP $\rightleftharpoons$ E+P
• B. E + S $\to$ EP
• C. E + S $\rightleftharpoons$ ES $\rightleftharpoons$ E+P
• D. Both A and C

Answer 1

Answer: (A)

E + S $\rightleftharpoons$ ES $\to$ EP $\rightleftharpoons$ E+P

• The active site of enzymes has a specific conformation for attracting and holding substrate. It usually possesses a service where the substrate fits in a complementary fashion. The two join to form a complex, i.e., enzyme-substrate complex.
• The complex state is short-lived. The substrate change into products. The products remain complexed with the active site of the enzyme for a short period. They soon separate and the active site is released to perform another catalytic act.

So, the correct option is A.