Question

Choose the correct option regarding the Assertion and Reason:

Assertion [A]: Patients having Klinefelter syndrome have higher amounts of estrogen in the body.
Reason [R]: Klinefelter syndrome occurs due to appearance of an extra X chromosome in the human males.

• A. Assertion [A] is True and Reason [R] is False.
• B. Reason [R] is True and Assertion [A] is False.
• C. Assertion [A] is True and Reason [R] is True and is a correct explanation for [A].
• D. Assertion [A] is True and Reason [R] is True but is an incorrect explanation to [A].

Answer 1

The correct option is C

Assertion [A] is True and Reason [R] is True and is a correct explanation for [A].

Klinefelter syndrome is a genetic disorder wherein a human male is born with an extra X chromosome in the cells (due to nondisjunction of X chromosomes, and the egg carrying XX getting fertilised by a Y carrying sperm), resulting in a total of 47 chromosomes - XXY. The additional X chromosome leads to severe hormonal imbalance. The patient would have lesser amount of testosterone in the body and higher production of estrogen, resulting in sterility and poor development of male secondary sexual characters.