The correct option is A Macrophage ingestion → Helper T cell activation → B cell activation → clonal formation
Bacteria are microscopic, single-cell organisms that live in every climate and location on earth. While some are airborne, others live in water or soil. These organisms live on and inside plants, animals, as well as human beings. Bacterial infection refers to the proliferation of a harmful strain of bacteria on or inside the body and infects any area of the body. Commonly caused infections are Pneumonia, meningitis, and food poisoning. Every infection has a chain of events which involves the infectious agent, reservoir, entering a susceptible host, exit, and transmission to new hosts. Each of the links must be present in a chronological order for an infection to develop. The infection starts, when bacteria successfully enters the body, grows and multiplies. This is referred to as colonization. Human beings response to bacterial infection begins with the initial phase and activation of the innate immune system, uptake of antigen is take place by macrophage, T-cells priming and promoting inflammation, the release of macrophages into the blood stream, B cell activation and differentiation and encapsulation of the bacteria. Thus, the correct answer is option A.