Question

Choose the correct statements regarding genetic disorders.
(I) Turner's female is a result of aneuploidy.
(II) Tritanopia is a sex-linked recessive disorder.

(III) Haemophilia C follows criss-cross pattern of inheritance.
(IV) Sickle cell anaemia is due to mutation of alleles on chromosome 11.

• A. I, IV
• B. II, III
• C. I, III, IV
• D. II, IIV

Answer 1

The correct option is C I, III, IV

Turner syndrome is a condition in human females where monosomy of X chromosome occurs. It results due to aneuploidy, abnormal number of chromosomes. Tritanopia is a disorder in which a person cannot differentiate between blue and yellow colors. It is an autosomal dominant disorder affecting both male and female equally. In criss cross pattern of inheritance, the trait is transferred from mother to son and from father to daughter. Haemophilia C is an X-linked disorder showing this type of inheritance. Sickle cell anaemia is caused due to the mutation in gene located on chromosome 11. The mutation causes change of amino acid from glutamic acid to valine.

Thus, the correct answer is option C.