Question

Choose the incorrect statement(s) with respect to ES cells used in production of transgenic mice.
I. ES cells are derived from inner cell mass of the zygote
II. ES cells can be cultured in vitro
III. ES cells are fast dividing

• A. I and II
• B. II only
• C. III only
• D. I only

Answer 1

The correct option is D I only

ES cells refer to embryonic stem cells. For mouse transgenesis, DNA is generally into the mice by introduction of genetically engineered embryonic stem cells into an early stage developing embryo. ES cells are derived from blastocyst and the single-celled zygote. ES cells can be cultured in vitro and are fast dividing if conditions are suitable.