Question

Choose the steps of glycolysis where substrate level phosphorylation occurs:
(a) Glucose $\to$ Glucose-6-phosphate
(b) $1,3$-bisphosphoglyceric acid $\to$ 3-phosphoglyceric acid
(c) $1,3$-bisphosphoglyceraldehyde $\to$ $1,3,$-bisphosphoglyceric acid
(d) Phosphoenolpyruvate $\to$ Pyruvate
(e) Fructose-6-phosphate $\to$ Fructose-$1,6$-bisphosphate

• A. a, e
• B. a, c
• C. b, d
• D. a, b, d, e

Answer 1

The correct option is C b, d

Substrate level phosphorylation is a process of formation of ATP from ADP and a phosphorylated intermediate (compound containing a phosphate group). In the process of breakdown of glucose into pyruvate called glycolysis, these are the following steps that involve substrate level phosphorylation:
i) $1,3$-bisphosphoglyceric acid $\to$ 3-phosphoglyceric acid
ii) Phosphoenolpyruvate $\to$ Pyruvate